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List of substances for condition Group: Heart

All Human Animal Risk/Association ReviewRows: 511

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Resveratrol 📋✍⛔38656259Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation
Ginsenosides 📋✍⛔38677536Ginsenoside Rb1 ameliorates lipotoxicity-induced myocardial injury in diabetes mellitus by regulating Mfn2
Melatonin 📋✍⛔38580195Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy
Curcumin 📋✍⛔38723524Cardioprotective effects of curcumin against Diabetic Cardiomyopathies: A systematic review and meta-analysis of preclinical studies
Omega-3 Fatty Acids 📋✍⛔38550520Decreased circulating omega-3 fatty acids increase the risk of myocardial infarction: a two-sample Mendelian randomization study
Vitamin D3 📋✍⛔38672124Vitamin D and Cardiovascular Diseases: From Physiology to Pathophysiology and Outcomes
Astragalosides 📋✍⛔38718959Integrative transcriptomics and proteomics analysis reveal the protection of Astragaloside IV against myocardial fibrosis by regulating senescence
Berberine 📋✍⛔38577949Berberine inhibits excessive autophagy and protects myocardium against ischemia/reperfusion injury via the RhoE/AMPK pathway
Ginseng 📋✍⛔38465214Ginseng and ginsenosides on cardiovascular and pulmonary diseases; Pharmacological potentials for the coronavirus (COVID-19)
Quercetin 📋✍⛔38716618Quercetin Ameliorates Myocardial Injury in Diabetic Rats by Regulating Autophagy and Apoptosis through AMPK/mTOR Signaling Pathway
CoQ10 📋✍⛔38710284Coenzyme Q10 mitigates cadmium cardiotoxicity by downregulating NF-κB/NLRP3 inflammasome axis and attenuating oxidative stress in mice
Puerarin 📋✍⛔38282474Puerarin inhibits NHE1 activity by interfering with the p38 pathway and attenuates mitochondrial damage induced by myocardial calcium overload in heart failure rats
EGCG 📋✍⛔38574620Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via modulation of 14-3-3η
Metformin 📋✍⛔38487671Metformin Inhibits Autophagy, Mitophagy and Antagonizes Doxorubicin-Induced Cardiomyocyte Death
Vitamin C 📋✍⛔38643461High-dose Vitamin C injection ameliorates against sepsis induced myocardial injury by anti-apoptosis, anti-inflammatory and pro-autophagy through regulating MAPK, NF-κB and PI3K/AKT/mTOR signaling pathways in rats
Magnesium 📋✍⛔37242238Magnesium Deficiency and Cardiometabolic Disease
Salidroside 📋 38552436Salidroside pretreatment alleviates ferroptosis induced by myocardial ischemia/reperfusion through mitochondrial superoxide-dependent AMPKα2 activation
Wenxin Keli 📋✍⛔36212955Effect of WenXin KeLi on Improvement of Arrhythmia after Myocardial Infarction by Intervening PI3K-AKT-mTOR Autophagy Pathway
Astaxanthin 📋✍⛔38296564Astaxanthin Alleviates the Process of Cardiac Hypertrophy by Targeting the METTL3/Circ_0078450/MiR-338-3p/GATA4 Pathway
L-Carnitine 📋✍⛔38568244L-carnitine decreases myocardial injury in children undergoing open-heart surgery: A randomized controlled trial
Luteolin 📋✍⛔38077523Luteolin Pretreatment Ameliorates Myocardial Ischemia/Reperfusion Injury by lncRNA-JPX/miR-146b Axis
Lycopene 📋✍⛔38264195Association between ischemic heart disease and dietary intake of lycopene: a case-control study
Tanshinone 📋 38419127The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia-reperfusion injury by inhibiting the STING pathway
Allicin 📋✍⛔38460945Allicin treats myocardial infarction in I/R through the promotion of the SHP2 axis to inhibit p-PERK-mediated oxidative stress
Cocoa 📋✍⛔37324470Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice
Ginkgo Biloba 📋✍⛔38718890Efficacy and Safety of Ginkgo biloba Extract in the Treatment of Unstable Angina Pectoris: A Systematic Review and Network Meta-Analysis
Hawthorn 📋✍⛔38732560Characterizations of White Mulberry, Sea-Buckthorn, Garlic, Lily of the Valley, Motherwort, and Hawthorn as Potential Candidates for Managing Cardiovascular Disease-In Vitro and Ex Vivo Animal Studies
Salvianolic Acid 📋 38662612SALVIANOLIC ACID A ATTENUATES ANGIOTENSIN II-INDUCED CARDIAC FIBROSIS THROUGH REGULATING THE TXNIP SIGNALING PATHWAY
Selenium 📋✍⛔38171821Impact of Selenium Deficiency on Clinical Outcomes in Newly Diagnosed Heart Failure Patients in Japan
Vitamin E 📋✍⛔38046702Vitamin E Supplementation and Cardiovascular Health: A Comprehensive Review
Shensong Yangxin 📋✍ 38305401The Different Therapeutic Effects of Traditional Chinese Medicine Shensong Yangxin Capsule and Salubrinal in High-intensity Exercise-induced Heart Failure in Rats with Acute Myocardial Infarction
Lipoic Acid 📋✍⛔38484905Impact of combined alpha-lipoic acid and mitoquinone supplementation on myocardial infarction in aged rats: Heart performance and molecular mechanisms
N-Acetyl Cysteine 📋✍⛔38647950N-acetylcysteine Protects Against Myocardial Ischemia-Reperfusion Injury Through Anti-ferroptosis in Type 1 Diabetic Mice
Eicosapentaenoic Acid 📋✍⛔38161115Effect of omega-3 fatty acids supplementation on the prognosis of coronary artery disease: A meta-analysis of randomized controlled trials
Garlic 📋✍⛔38732560Characterizations of White Mulberry, Sea-Buckthorn, Garlic, Lily of the Valley, Motherwort, and Hawthorn as Potential Candidates for Managing Cardiovascular Disease-In Vitro and Ex Vivo Animal Studies
Gingerol 📋✍ 366248786-Gingerol Alleviates Ferroptosis and Inflammation of Diabetic Cardiomyopathy via the Nrf2/HO-1 Pathway
Modified Citrus Pectin 📋✍⛔38522819Effect of modified citrus pectin on galectin-3 inhibition in cisplatin-induced cardiac and renal toxicity
Nicotinamide Riboside 📋✍⛔38703508Nicotinamide riboside attenuates myocardial ischemia-reperfusion injury via regulating SIRT3/SOD2 signaling pathway
Red Sage 📋✍⛔38641076Salvia miltiorrhiza suppresses cardiomyocyte ferroptosis after myocardial infarction by activating Nrf2 signaling
Sulforaphane 📋✍⛔37906532Sulforaphane ameliorate Arsenic induced cardiotoxicity in rats: Role of PI3k/Akt mediated Nrf2 signaling pathway
Asiatic Acid 📋 37717794Asiatic acid protects against pressure overload-induced heart failure in mice by inhibiting mitochondria-dependent apoptosis
Cannabidiol 📋✍⛔38401641Investigation of neuroprotective and therapeutic effects of cannabidiol in an acute coronary syndrome model
Crocin 📋✍⛔38113243Effect of crocin and treadmill exercise on oxidative stress and heart damage in diabetic rats
L-Arginine 📋✍⛔38428781Alleviation of albumin glycation-induced diabetic cardiomyopathy by L-Arginine: Insights into Nrf-2 signaling
Apigenin 📋✍⛔37928261Screening of an FDA-approved compound library identifies apigenin for the treatment of myocardial injury
Grape Seed extract 📋✍⛔37555371Protective effect of grape seed extract and exercise training on tissues toxicities in doxorubicin-treated healthy rat
Medicinal Plants 📋 38464786The potential of herbal drugs to treat heart failure: The roles of Sirt1/AMPK
Naringenin 📋✍⛔38387325Naringenin protects against septic cardiomyopathy in mice by targeting HIF-1α
Rutin 📋✍⛔37599700The effects of rutin supplement on blood pressure markers, some serum antioxidant enzymes, and quality of life in patients with type 2 diabetes mellitus compared with placebo
Astragalus Root 📋✍⛔38386515Pharmacodynamics and mechanism of Astragali radix and Anemarrhenae rhizoma in treating chronic heart failure by inhibiting complement activation
Fisetin 📋✍⛔37880513DNA hypomethylation by fisetin preserves mitochondria functional genes and contributes to the protection of I/R rat heart
Coffee 📋✍⛔38186410Is Coffee and Tea a Threat or Ally to Cardiovascular Health?
Food 📋 38103377A low-carbohydrate diet in place of SGLT2i therapy in a patient with diabetic cardiomyopathy
Olive Oil 📋✍⛔38568797Olive oil intake and cardiovascular disease, cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies
Baicalein 📋✍⛔38547614Baicalein alleviates cardiomyocyte death in EAM mice by inhibiting the JAK-STAT1/4 signalling pathway
Docosahexaenoic Acid 📋✍⛔38303014Association of dietary fats with ischemic heart disease (IHD): a case-control study
Ellagic Acid 📋✍⛔38356441Ellagic acid protects against angiotensin II-induced hypertrophic responses through ROS-mediated MAPK pathway in H9c2 cells
Fish Oil 📋✍⛔37999373Cardiovascular Diseases and Marine Oils: A Focus on Omega-3 Polyunsaturated Fatty Acids and Polar Lipids
Gallic Acid 📋 ⛔38252301The protective effects of gallic acid and SGK1 inhibitor on cardiac damage and genes involved in Ca2+ homeostasis in an isolated heart model of ischemia/reperfusion injury in rat
Hesperidin 📋✍⛔38292716The role of hesperidin as a cardioprotective strategy against doxorubicin-induced cardiotoxicity: The antioxidant, anti-inflammatory, antiapoptotic, and cytoprotective potentials
Thymoquinone 📋 ⛔36547425Effects of Thymoquinone Alone or in Combination with Losartan on the Cardiotoxicity Caused by Oxidative Stress and Inflammation in Hypercholesterolemia
Arjuna 📋✍⛔37497554Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway
Goji Berry 📋✍⛔38493701Lycium barbarum polysaccharide's protective effects against PM2.5-induced cellular senescence in HUVECs
Metoprolol 📋✍⛔37122993Evaluation of metoprolol standard dosing pathway in Chinese patients with acute coronary syndrome: a prospective multicenter single-arm interventional study
Naringin 📋✍⛔38501506Naringin activates semaphorin 3A to ameliorate TGF-β-induced endothelial-to-mesenchymal transition related to atrial fibrillation
NMN 📋✍⛔38422177Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis
Nobiletin 📋✍ 37146415Nobiletin alleviates myocardial ischemia-reperfusion injury via ferroptosis in rats with type-2 diabetes mellitus
Wine 📋 ⛔38001889Resveratrol and beyond: The Effect of Natural Polyphenols on the Cardiovascular System: A Narrative Review
Pterostilbene 📋✍⛔38573589EFFECTS OF PTEROSTILBENE ON HEART AND LUNG OXIDATIVE STRESS PARAMETERS IN TWO EXPERIMENTAL MODELS OF CARDIOVASCULAR DISEASE: MYOCARDIAL INFARCTION AND PULMONARY ARTERIAL HYPERTENSION
Taurine 📋✍⛔38612980Short Communication: Taurine Long-Term Treatment Prevents the Development of Cardiac Hypertrophy, and Premature Death in Hereditary Cardiomyopathy of the Hamster Is Sex-Independent
Zinc 📋✍⛔38036071Dietary antioxidant intake reduces carotid intima-media thickness in coronary heart disease patients: From the CORDIOPREV study
Andrographolide 📋 38400848An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Andrographolide in Doxorubicin-Induced Cardiotoxicity
Dihydromyricetin 📋✍⛔38596141Dihydromyricetin regulates RIPK3-CaMKII to prevent necroptosis in high glucose-stimulated cardiomyocytes
Ginkgolides 📋 38125702Ginkgolide B Blocks Vascular Remodeling after Vascular Injury via Regulating Tgf β 1/Smad Signaling Pathway
Icariin 📋✍ 38115154Icariin improves cardiac function and remodeling via the TGF-β1/Smad signaling pathway in rats following myocardial infarction
Micronutrients 📋 ⛔37274126Cardiovascular aging: from cellular and molecular changes to therapeutic interventions
Genistein 📋✍⛔37275572Pharmacological Effects of Genistein on Cardiovascular Diseases
Calycosin 📋 38576421Exploring the effects of calycosin on anthracycline-induced cardiotoxicity: a network pharmacology, molecular docking, and experimental study
Emodin 📋 ⛔38507311Emodin ameliorates myocardial fibrosis in mice by inactivating the ROS/PI3K/Akt/mTOR axis
Fucoidan 📋✍⛔38462108A synergistic strategy based on active hydroxymethyl amine compounds and fucoidan for bioprosthetic heart valves with enhancing anti-coagulation and anti-calcification properties
Kaempferol 📋✍⛔37879426Kaempferol protects against cardiovascular abnormalities induced by nitric oxide deficiency in rats by suppressing the TNF-α pathway
Oleuropein 📋 38589925Oleuropein alleviates myocardial ischemia-reperfusion injury by suppressing oxidative stress and excessive autophagy via TLR4/MAPK signaling pathway
Phytochemicals 📋 38377736Targeting the JAK2/STAT3 signaling pathway with natural plants and phytochemical ingredients: A novel therapeutic method for combatting cardiovascular diseases
Aged Garlic 📋✍⛔36825728Organosulfur Compounds in Aged Garlic Extract Ameliorate Glucose Induced Diabetic Cardiomyopathy by Attenuating Oxidative Stress, Cardiac Fibrosis, and Cardiac Apoptosis
Almond 📋 ⛔34057922Almond protects the liver in coronary artery disease: A randomized controlled clinical trial
Baicalin 📋✍⛔38712979Baicalin alleviates angiotensin II-induced cardiomyocyte apoptosis and autophagy and modulates the AMPK/mTOR pathway
Ferulic Acid 📋✍⛔38223449Integrated mass spectrometry imaging reveals spatial-metabolic alteration in diabetic cardiomyopathy and the intervention effects of ferulic acid
Hesperetin 📋 37866951[Hesperetin Alleviates Doxorubicin-Induced Cytotoxicity in H9c2 Cells by Activating SIRT1/NRF2 Signaling]
Acacetin 📋 37348478Acacetin alleviates cardiac fibrosis via TGF-β1/Smad and AKT/mTOR signal pathways in spontaneous hypertensive rats
Acetyl-L-Carnitine 📋✍⛔36537638[Antiastenic effect of sequential levocarnitine and acetylcarnitine therapy in patients with cardiovascular diseases]
Green Tea 📋✍⛔38308353Green tea consumption and incidence of cardiovascular disease in type 2 diabetic patients with overweight/obesity: a community-based cohort study
Irisin 📋 38663105New insights into the roles of Irisin in diabetic cardiomyopathy and vascular diseases
NAD 📋 38357951The Role of NAD+ in Myocardial Ischemia-induced Heart Failure in Sprague-Dawley Rats and Beagles
Nigella Sativa 📋✍⛔36062712Prevention of doxorubicin-induced experimental cardiotoxicity by Nigella sativa in rats
Nuts 📋 ⛔38254543The Cardioprotective Properties of Selected Nuts: Their Functional Ingredients and Molecular Mechanisms
Rapamycin 📋✍ 37893908Multi-Omic, Histopathologic, and Clinicopathologic Effects of Once-Weekly Oral Rapamycin in a Naturally Occurring Feline Model of Hypertrophic Cardiomyopathy: A Pilot Study
Reishi Mushrooms 📋✍⛔37033616Ganoderma lucidum polysaccharides attenuates pressure-overload-induced pathological cardiac hypertrophy
Spikenard 📋✍⛔36408810Total saponins of Aralia elata (Miq.) Seem. alleviate myocardial ischemia-reperfusion injury by promoting NLRP3-inflammasome inactivation via PI3K/Akt signaling
Vitamin B6 📋✍⛔38034370Intakes of folate, vitamin B6, and vitamin B12 and cardiovascular disease risk: a national population-based cross-sectional study
Vitamin B9 📋✍⛔38261080Effect of folic acid on isoprenaline-induced myocardial injury in rats
Walnut 📋 ⛔36213224Walnut supplementation after fructose-rich diet is associated with a beneficial fatty acid ratio and increased ACE2 expression in the rat heart
Alpha-Linolenic Acid 📋✍⛔38117698Association between dietary omega-3 intake and coronary heart disease among American adults: The NHANES, 1999-2018
Aspirin 📋 ⛔37713477Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease and Diabetes Mellitus: A Subgroup Analysis of the ADAPTABLE Trial
Beets 📋✍⛔38472804The Cardioprotective Role of Nitrate-Rich Vegetables
Chokeberry 📋✍⛔35563943Aronia melanocarpa Fruit Juice Modulates ACE2 Immunoexpression and Diminishes Age-Related Remodeling of Coronary Arteries in Rats
Chrysin 📋✍⛔35943656Chrysin protects cardiac H9c2 cells against H 2 O 2-induced endoplasmic reticulum stress by up-regulating the Nrf2/PERK pathway
Crocetin 📋 38675456Preventive and Therapeutic Effects of Crocetin in Rats with Heart Failure
Honokiol 📋 37985436Honokiol ameliorates angiotensin II-induced cardiac hypertrophy by promoting dissociation of the Nur77-LKB1 complex and activating the AMPK pathway
Liquiritin 📋 38361515Mechanistic investigation of the ameliorative effect of liquiritin on hypoxia/reoxygenation‑induced cardiomyocyte injury based on network pharmacology and in vitro validation
Paeoniflorin 📋 38427210Paeoniflorin attenuates cuproptosis and ameliorates left ventricular remodeling after AMI in hypobaric hypoxia environments
Polyphenols 📋 37998340Doxorubicin-Induced Cardiac Senescence Is Alleviated Following Treatment with Combined Polyphenols and Micronutrients through Enhancement in Mitophagy
Schisandrins 📋 36660202Schisandrin B Alleviates Diabetic Cardiac Autonomic neuropathy Induced by P2X7 Receptor in Superior Cervical Ganglion via NLRP3
Glycyrrhizic Acid 📋✍⛔38185229Glycyrrhizic acid alleviated MI/R-induced injuries by inhibiting Hippo/YAP signaling pathways
Grape 📋 ⛔34805304Antioxidant/Pro-Oxidant Actions of Polyphenols From Grapevine and Wine By-Products-Base for Complementary Therapy in Ischemic Heart Diseases
Moringa Oleifera 📋✍⛔37525636Moringa oleifera Leaves Extract Ameliorates Doxorubicin-Induced Cardiotoxicity via Its Mitochondrial Biogenesis Modulatory Activity in Rats
Piperine 📋✍⛔33732347Piperine protects against myocardial ischemia/reperfusion injury by activating the PI3K/AKT signaling pathway
Schisandra 📋✍⛔37006723Investigating the Mechanism of Action of Schisandra chinensis Combined with Coenzyme Q10 in the Treatment of Heart Failure Based on PI3K-AKT Pathway
Sea Buckthorn 📋✍⛔38732560Characterizations of White Mulberry, Sea-Buckthorn, Garlic, Lily of the Valley, Motherwort, and Hawthorn as Potential Candidates for Managing Cardiovascular Disease-In Vitro and Ex Vivo Animal Studies
Tea 📋 38604951[Association between habitual tea consumption and 10-year cardiovascular risk among Chinese mid-aged and elderly]
TUDCA 📋✍⛔33307852Inhibition of Brainstem Endoplasmic Reticulum Stress Rescues Cardiorespiratory Dysfunction in High Output Heart Failure
Acai Berry 📋✍⛔37626388Euterpe oleracea extract (açaí) exhibits cardioprotective effects after chemotherapy treatment in a breast cancer model
Anthocyanins 📋✍⛔36355516The Role of Anthocyanin in Modulating Diabetic Cardiovascular Disease and Its Potential to Be Developed as a Nutraceutical
Carvacrol 📋✍⛔38726397Protective effects of carvacrol on lipid profiles, oxidative stress, hypertension, and cardiac dysfunction - A comprehensive review
Flavonoids 📋 ⛔38729253Molecular mechanisms of flavonoids in myocardial ischemia reperfusion injury: Evidence from in-vitro and in-vivo studies
Hydroxytyrosol 📋 36912212Association of hydroxytyrosol enriched olive oil with vascular function in chronic coronary disease
Mangiferin 📋 ⛔37615589Mangiferin Protects Against Angiotensin-II-Enhanced Hypertrophic Markers and Apoptosis in H9c2 Cardiomyocytes
Ollive Leaf extract 📋✍⛔38722494Simultaneous Exposure to Noise and Toluene Induces Oxidative and Inflammatory Damage in the Heart of Wistar Rats: Therapeutic Potential of Olea europaea L. Leaf Extract
Paeonol 📋 38593570Paeonol can improve hypoxic-induced H9c2 cells injury and ion channel activity by up-regulating the expression of CKIP-1
PUFA 📋 37644429Associations of polyunsaturated fatty acids with cardiovascular disease and mortality: a study of NHANES database in 2003-2018
Saffron 📋✍⛔36570145The effects of saffron supplementation on cardiovascular risk factors in adults: A systematic review and dose-response meta-analysis
Trehalose 📋 ⛔37469485Effect of trehalose on heart functions in rats model after myocardial infarction: assessment of novel intraventricular pressure and heart rate variability
Carnosic Acid 📋 38419896Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations
Cinnamaldehyde 📋 38404216Cinnamaldehyde protects cardiomyocytes from oxygen-glucose deprivation/reoxygenation-induced lipid peroxidation and DNA damage via activating the Nrf2 pathway
Citicoline 📋✍⛔34866692Serum Levels of the Biomarkers Associated with Astrocytosis, Neurodegeneration, and Demyelination: Neurological Benefits of Citicoline Treatment of Patients with Ischemic Stroke and Atrial Fibrillation
DHEA 📋✍⛔37391895Serum DHEA and Testosterone Levels Associate Inversely with Coronary Artery Calcification in Elderly Men
Dihydroquercetin 📋 38053888Taxifolin protects against doxorubicin-induced cardiotoxicity and ferroptosis by adjusting microRNA-200a-mediated Nrf2 signaling pathway
Fish 📋 ⛔37820771Fish consumption and its lipid modifying effects - A review of intervention studies
Flaxseed Oil 📋✍⛔38167049Flaxseed oil fraction reverses cardiac remodeling at a molecular level: improves cardiac function, decreases apoptosis, and suppresses miRNA-29b and miRNA 1 gene expression
Fucoxanthin 📋✍⛔37861458Fucoxanthin alleviated myocardial ischemia and reperfusion injury through inhibition of ferroptosis via the NRF2 signaling pathway
Galangin 📋 37655750Galangin attenuates doxorubicin-induced cardiotoxicity via activating nuclear factor erythroid 2-related factor 2/heme oxygenase 1 signaling pathway to suppress oxidative stress and inflammation
Lemon Balm 📋✍⛔35890139Short-Term Administration of Lemon Balm Extract Ameliorates Myocardial Ischemia/Reperfusion Injury: Focus on Oxidative Stress
Silibinin 📋✍ 37165384A systematic review of the protective effects of silymarin/silibinin against doxorubicin-induced cardiotoxicity
Silymarin 📋✍⛔38675181Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress
Tomato 📋 ⛔36615701In-Season Consumption of Locally Produced Tomatoes Decreases Cardiovascular Risk Indices
Vitamin B12 📋✍⛔38645491Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats
Angelica 📋✍⛔38731591Research Progress in Pharmacological Effects and Mechanisms of Angelica sinensis against Cardiovascular and Cerebrovascular Diseases
Antioxidants 📋 ⛔38036071Dietary antioxidant intake reduces carotid intima-media thickness in coronary heart disease patients: From the CORDIOPREV study
Black Tea 📋✍⛔38161525Impact of Green Tea Consumption on the Prevalence of Cardiovascular Outcomes: A Systematic Review
Chlorogenic Acid 📋✍⛔38398512Chlorogenic Acid Attenuates Isoproterenol Hydrochloride-Induced Cardiac Hypertrophy in AC16 Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway
Cinnamon 📋✍⛔36873789Exploring Myocardial Ischemia-Reperfusion Injury Mechanism of Cinnamon by Network Pharmacology, Molecular Docking, and Experiment Validation
Coconut Oil 📋 ⛔37397927Cardioprotective role of the coenzyme Q10 and coconut oil in acute aluminum phosphide poisoning: a randomized controlled clinical trial
Dioscin 📋 38672439Protective Role of Dioscin against Doxorubicin-Induced Chronic Cardiotoxicity: Insights from Nrf2-GPX4 Axis-Mediated Cardiac Ferroptosis
Flaxseed 📋✍⛔37778442Effect of alpha-linolenic acid supplementation on cardiovascular risk profile in individuals with obesity or overweight: A systematic review and meta-analysis of randomized controlled trials
Hyperoside 📋 38518637Exploring the role and mechanism of hyperoside against cardiomyocyte injury in mice with myocardial infarction based on JAK2/STAT3 signaling pathway
Lutein 📋✍⛔37797674Lutein suppresses ferroptosis of cardiac microvascular endothelial cells via positive regulation of IRF in cardiac hypertrophy
Rosmarinic Acid 📋✍ 38372095Rosmarinic acid attenuates TNF-α induced cardiomyocyte injury via regulating miR-344a-3p
Scutellarin 📋 38259289Effects of scutellarin on the mechanism of cardiovascular diseases: a review
Spermidine 📋 38293988[Spermidine alleviates lipopolysaccharide-induced myocardial injury in mice by suppressing apoptosis, ROS production and ferroptosis]
Tribulus Terrestris 📋✍⛔35283118Synchronized resistance training and bioactive herbal compounds of Tribulus Terrestris reverse the disruptive influence of Stanozolol
Vitamin B1 📋✍⛔37720374Association of vitamin B1 with cardiovascular diseases, all-cause and cardiovascular mortality in US adults
Vitamin K2 📋✍⛔36039403Role of vitamin K2 in bone-vascular crosstalk
Wogonin 📋✍⛔35770725Wogonin Ameliorated Obesity-Induced Lipid Metabolism Disorders and Cardiac Injury via Suppressing Pyroptosis and Deactivating IL-17 Signaling Pathway
Zingerone 📋 37240920Trastuzumab-Mediated Cardiotoxicity and Its Preventive Intervention by Zingerone through Antioxidant and Inflammatory Pathway in Rats
Aloin 📋 37950500SNHG1/miR-21 axis mediates the cardioprotective role of aloin in sepsis through modulating cardiac cell viability and inflammatory responses
Apple 📋 ⛔34565081Apple or apple polyphenol consumption improves cardiovascular disease risk factors: a systematic review and meta-analysis
Berries 📋 35300756Effects of Anthocyanin-rich Berries on the Risk of Metabolic Syndrome: A Systematic Review and Meta-analysis
Capsaicin 📋✍⛔38481548Phytoformulation with hydroxycitric acid and capsaicin protects against high-fat-diet-induced obesity cardiomyopathy by reducing cardiac lipid deposition and ameliorating inflammation and apoptosis in the heart
Cheese 📋 ⛔37671505High consumption of dairy products and risk of major adverse coronary events and stroke in a Swedish population
Dandelion 📋✍⛔36986458New Approaches on the Anti-Inflammatory and Cardioprotective Properties of Taraxacum officinale Tincture
Diosmin 📋✍⛔35522359Investigating Radioprotective Effect of Hesperidin/Diosmin Compound Against 99m Tc-MIBI-Induced Cardiotoxicity: Animal Study
Geniposide 📋 37682077Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway
Ginger 📋✍⛔36500700Cardioprotective Effects of 6-Gingerol against Alcohol-Induced ROS-Mediated Tissue Injury and Apoptosis in Rats
Green Tea Polyphenols 📋✍⛔36355510In Vivo Treatment with a Standardized Green Tea Extract Restores Cardiomyocyte Contractility in Diabetic Rats by Improving Mitochondrial Function through SIRT1 Activation
Indian Gooseberry 📋 ⛔37296402Clinical effects of Emblica officinalis fruit consumption on cardiovascular disease risk factors: a systematic review and meta-analysis
Licorice Root 📋✍⛔37308027Anti-arrhythmia potential of honey-processed licorice in zebrafish model: Antioxidant, histopathological and tissue distribution
Myricetin 📋 ⛔38472186Myricetin alleviates diabetic cardiomyopathy by regulating gut microbiota and their metabolites
Peanut 📋 ⛔34496618Peanut Consumption and Risk of Stroke and Ischemic Heart Disease in Japanese Men and Women: The JPHC Study
Raspberry 📋✍⛔37984734Raspberry Polyphenols Target Molecular Pathways of Heart Failure
Rhodiola 📋✍⛔38505080Investigating the multitarget pharmacological mechanism of Rhodiola wallichiana var. cholaensis acting on angina pectoris using combined network pharmacology and molecular docking
Roselle 📋✍⛔37375755Therapeutic Potential of Hibiscus sabdariffa Linn. in Attenuating Cardiovascular Risk Factors
Safflower 📋✍⛔37258471The Cardioprotective Effects and Mechanisms of Astragalus-Safflower Herb Pairs on Coronary Heart Disease Identified by Network Pharmacology and Experimental Verification
Spirulina 📋✍⛔38474769Beneficial Effects of Spirulina Supplementation in the Management of Cardiovascular Diseases
Vitamin K 📋✍⛔34688697Vitamin K: A vital micronutrient with the cardioprotective potential against diabetes-associated complications
Aloe-Emodin 📋 37364691Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis
Amygdalin 📋✍⛔38529199Beneficial role of amygdalin extracts against animal growth regulator Boldjan induced cardiac toxicity, injury and oxidative stress in male rats
Andrographis 📋✍⛔34990768Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia
Arctigenin 📋 33574759AMPK/SIRT1 Pathway is Involved in Arctigenin-Mediated Protective Effects Against Myocardial Ischemia-Reperfusion Injury
Bee Propolis 📋✍⛔38556227Propolis in the management of cardiovascular disease
Bergamot 📋✍⛔34371986Effects of Bergamot Polyphenols on Mitochondrial Dysfunction and Sarcoplasmic Reticulum Stress in Diabetic Cardiomyopathy
Biochanin A 📋 38091641Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro
Carotenoids 📋✍⛔38036071Dietary antioxidant intake reduces carotid intima-media thickness in coronary heart disease patients: From the CORDIOPREV study
Catechins 📋 36558031Health Effects of Soy Isoflavones and Green Tea Catechins on Cancer and Cardiovascular Diseases Based on Urinary Biomarker Levels
Cranberry 📋✍⛔37823158The role of alcohol extract of cranberry in improving serum indices of experimental metaproterenol-induced heart damage in rats
Iron 📋✍⛔37722377Iron deficiency in myocardial ischemia: molecular mechanisms and therapeutic perspectives
L-Citrulline 📋✍⛔36904267Dietary Arginine and Citrulline Supplements for Cardiovascular Health and Athletic Performance: A Narrative Review
Magnolol 📋 37074505Cardioprotective role of a magnolol and honokiol complex in the prevention of doxorubicin-mediated cardiotoxicity in adult rats
Orange 📋 ⛔34265580Pera orange (Citrus sinensis) and Moro orange (Citrus sinensis (L.) Osbeck) juices attenuate left ventricular dysfunction and oxidative stress and improve myocardial energy metabolism in acute doxorubicin-induced cardiotoxicity in rats
Pomegranate 📋 ⛔29998575Nitric oxide plays a pivotal role in cardioprotection induced by pomegranate juice against myocardial ischemia and reperfusion
Pomegranate Peel extract 📋✍⛔37376144Pomegranate Peel Extract Attenuates Isoprenaline-Induced Takotsubo-like Myocardial Injury in Rats
Probiotics 📋✍⛔38411391Advancing lifelong precision medicine for cardiovascular diseases through gut microbiota modulation
Punicalagin 📋✍⛔37806379Punicalagin attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats: Biochemical, immunohistochemical, and in silico molecular docking studies
Pyridoxal-5-Phosphate 📋✍⛔37946524Upregulation of ATP-Sensitive Potassium Channels as the Potential Mechanism of Cardioprotection and Vasorelaxation Under the Action of Pyridoxal-5-Phosphate in Old Rats
Senolytics 📋 38680957Cellular Senescence as a Targetable Risk Factor for Cardiovascular Diseases: Therapeutic Implications: JACC Family Series
Vitamin B2 📋✍⛔37377111Riboflavin protects against heart failure via SCAD-dependent DJ-1- Keap1-Nrf2 signaling pathway
Artemisinin 📋 38258596Artemisinin Attenuates Isoproterenol-induced Cardiac Hypertrophy via the ERK1/2 and p38 MAPK Signaling Pathways
Asiaticoside 📋 38113341Cardioprotective effects of asiaticoside against diabetic cardiomyopathy: Activation of the AMPK/Nrf2 pathway
Beta-Sitosterol 📋✍⛔38028434Inhibitory Effect of β-Sitosterol on the Ang II-Induced Proliferation of A7r5 Aortic Smooth Muscle Cells
Blueberry 📋✍⛔34988854Blueberry extract attenuates norepinephrine-induced oxidative stress and apoptosis in H9c2 cardiac cells
CAPE 📋 38474755Ethanolic Extract of Propolis and CAPE as Cardioprotective Agents against LPS and IFN-α Stressed Cardiovascular Injury
Choline 📋✍⛔38711145Dietary choline intake and health outcomes in U.S. adults: exploring the impact on cardiovascular disease, cancer prevalence, and all-cause mortality
Copper 📋✍⛔37447366Copper and Zinc Particles as Regulators of Cardiovascular System Function-A Review
Daidzein 📋✍⛔36541083Daidzein ameliorates doxorubicin-induced cardiac injury by inhibiting autophagy and apoptosis in rats
Diallyl Trisulfide 📋 38185348Diallyl trisulfide (DATS) protects cardiac cells against advanced glycation end-product-induced apoptosis by enhancing FoxO3A-dependent upregulation of miRNA-210
Echinacoside 📋 38125366Echinacoside ameliorates doxorubicin‑induced cardiac injury by regulating GPX4 inhibition‑induced ferroptosis
Eugenol 📋 38085446Targeting cardiovascular risk factors with eugenol: an anti-inflammatory perspective
Fiber 📋✍⛔38165561Relationship between dietary fiber and all-cause mortality, cardiovascular mortality, and cardiovascular disease in patients with chronic kidney disease: a systematic review and meta-analysis
Folate 📋✍⛔37707697Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer's Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways
Fruits 📋 38068771Vegetable and Fruit Intake Variety and Cardiovascular Health and Mortality: A Systematic Review and Meta-Analysis of Observational Studies
Kudzu Root 📋✍⛔38048301Effect of pueraria on left ventricular remodelling in HFrEF: A systematic review and meta-analysis
L-Leucine 📋✍⛔38165500Cardioprotective Effects of Leucine Supplementation against Doxorubicin-Induced Cardiotoxicit
Minerals 📋 37998340Doxorubicin-Induced Cardiac Senescence Is Alleviated Following Treatment with Combined Polyphenols and Micronutrients through Enhancement in Mitophagy
Neferine 📋 38526658Neferine Pretreatment Attenuates Isoproterenol-Induced Cardiac Injury Through Modulation of Oxidative Stress, Inflammation, and Apoptosis in Rats
Onion 📋✍⛔34400937Onion ( Allium cepa) and its Main Constituents as Antidotes or Protective Agents against Natural or Chemical Toxicities: A Comprehensive Review
Pine Bark 📋✍⛔35745592Protective Effect of Pycnogenol against Methotrexate-Induced Hepatic, Renal, and Cardiac Toxicity: An In Vivo Study
Polydatin 📋✍ 37168258Identification of cuproptosis-related biomarkers in dilated cardiomyopathy and potential therapeutic prediction of herbal medicines
Red Yeast Rice 📋✍⛔30953818Xuezhikang improves the outcomes of cardiopulmonary resuscitation in rats by suppressing the inflammation response through TLR4/NF-κB pathway
Seafood 📋 38161129Association of seafood consumption with cardiovascular disease among adults in Qingdao, China
Tetrahydrocurcumin 📋✍ 37812853Tetrahydrocurcumin ameliorates postinfarction cardiac dysfunction and remodeling by inhibiting oxidative stress and preserving mitochondrial function via SIRT3 signaling pathway
Betaine 📋✍⛔38703273Betaine Protects Mice from Cardiotoxicity Triggered by Sodium Arsenite Through Antioxidative and Anti-inflammatory Pathways
Bilberry 📋✍⛔32846041Bilberry Supplementation after Myocardial Infarction Decreases Microvesicles in Blood and Affects Endothelial Vesiculation
Caffeine 📋✍⛔37764216Potential Benefits of Coffee Consumption on Improving Biomarkers of Oxidative Stress and Inflammation in Healthy Individuals and Those at Increased Risk of Cardiovascular Disease
Catalpol 📋 38024856Protective effects of catalpol on cardio-cerebrovascular diseases: A comprehensive review
Cinnamic Acid 📋 37453198Cinnamic acid mitigates left ventricular hypertrophy and heart failure in part through modulating FTO-dependent N6-methyladenosine RNA modification in cardiomyocytes
Coptis Chinensis 📋 ⛔34221073LianXia Formula Granule Attenuates Cardiac Sympathetic Remodeling in Rats with Myocardial Infarction via the NGF/TrKA/PI3K/AKT Signaling Pathway
Cordycepin 📋 35352454Protective effects of cordycepin against d-galactose-induced aging in rats: A view from the heart
D-Ribose 📋✍⛔35644694Effects of Ubiquinol and/or D-ribose in Patients With Heart Failure With Preserved Ejection Fraction
Dairy 📋 37684008Whole-Milk Dairy Foods: Biological Mechanisms Underlying Beneficial Effects on Risk Markers for Cardiometabolic Health
Diosgenin 📋 38643718Diosgenin improves post-myocardial infarction cardiac function via HAND2-induced angiogenesis
Diosmetin 📋 37367046Antioxidant Flavonoid Diosmetin Is Cardioprotective in a Rat Model of Myocardial Infarction Induced by Beta 1-Adrenergic Receptors Activation
Escin 📋✍⛔35126791Effects of Escin on Oxidative Stress and Apoptosis of H9c2 Cells Induced by H 2 O 2
Fenugreek 📋✍⛔37885997Promoting cardioprotection with fenugreek: Insights from CoCl2-induced hypoxia in neonatal rat cardiomyocytes
Formononetin 📋 38070245Formononetin ameliorates isoproterenol induced cardiac fibrosis through improving mitochondrial dysfunction
Geraniol 📋 37226502Potential inhibitory effect of geraniol isolated from lemongrass ( Cymbopogon commutatus Stapf) on tilmicosin-induced oxidative stress in cardiac tissue
Gotu Kola 📋✍⛔35181485Centella asiatica (L.) Urb. attenuates cardiac hypertrophy and improves heart function through multi-level mechanisms revealed by systems pharmacology
Isoliquiritigenin 📋 37807075Deep learning-assisted high-content screening identifies isoliquiritigenin as an inhibitor of DNA double-strand breaks for preventing doxorubicin-induced cardiotoxicity
Isorhamnetin 📋 36540030Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation
Kiwifruit 📋✍⛔29750308Actinidia chinensis planch polysaccharide protects against hypoxia‑induced apoptosis of cardiomyocytes in vitro
L-Glutamine 📋✍⛔38013301The essential role of glutamine metabolism in diabetic cardiomyopathy: A review
Limonin 📋 37290669Limonin ameliorates cardiovascular dysfunction and remodeling in hypertensive rats
Lupeol 📋 37976692Lupeol alleviates autoimmune myocarditis by suppressing macrophage pyroptosis and polarization via PPARα/LACC1/NF-κB signaling pathway
Mulberry 📋 ⛔38732560Characterizations of White Mulberry, Sea-Buckthorn, Garlic, Lily of the Valley, Motherwort, and Hawthorn as Potential Candidates for Managing Cardiovascular Disease-In Vitro and Ex Vivo Animal Studies
Nattokinase 📋✍⛔35804683Recent Advances in Nattokinase-Enriched Fermented Soybean Foods: A Review
Nuciferine 📋 38528077Nuciferine reduces vascular leakage and improves cardiac function in acute myocardial infarction by regulating the PI3K/AKT pathway
Potassium 📋✍⛔38163867Effect of low sodium and high potassium diet on lowering blood pressure and cardiovascular events
PQQ 📋✍⛔36238573Pyrroloquinoline quinone modulates YAP-related anti-ferroptotic activity to protect against myocardial hypertrophy
Retinoic Acid 📋 36105385Therapeutic Effects of Retinoic Acid in Lipopolysaccharide-Induced Cardiac Dysfunction: Network Pharmacology and Experimental Validation
Sesamin 📋✍ 37357850Sesamin suppresses angiotensin-II-enhanced oxidative stress and hypertrophic markers in H9c2 cells
Soy 📋✍⛔38520523Associations of soy product intake with all-cause, cardiovascular disease and cancer mortality: Guangzhou Biobank Cohort Study and updated meta-analyses
Tangeretin 📋 33260422Cardioprotective Effect of Tangeretin by Inhibiting PTEN/AKT/mTOR Axis in Experimental Sepsis-Induced Myocardial Dysfunction
Urolithins 📋 37257327Promising remedies for cardiovascular disease: Natural polyphenol ellagic acid and its metabolite urolithins
Ursolic Acid 📋✍⛔37547335Ursolic acid reduces oxidative stress injury to ameliorate experimental autoimmune myocarditis by activating Nrf2/HO-1 signaling pathway
Valerian Root 📋✍⛔37908890CARDIOPROTECTIVE EFFECT OF DICHLOROMETHANE VALERIAN (VALERIANA OFFICINALIS) EXTRACT ON ISCHEMIA-REPERFUSION-INDUCED CARDIAC INJURIES IN RATS
Vegetables 📋 38068771Vegetable and Fruit Intake Variety and Cardiovascular Health and Mortality: A Systematic Review and Meta-Analysis of Observational Studies
Vitamin B Complex 📋 ⛔37850302The effect of B-vitamins on the prevention and treatment of cardiovascular diseases: a systematic review and meta-analysis
Vitamin B3 📋✍⛔35173682NAD+-Increasing Strategies to Improve Cardiometabolic Health?
Vitamin K1 📋✍⛔38342722Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women
Vitexin 📋 35254859Vitexin protects against high glucose-induced endothelial cell apoptosis and oxidative stress via Wnt/β-catenin and Nrf2 signalling pathway
Apple Polyphenols 📋 ⛔35268023Red-Fleshed Apples Rich in Anthocyanins and White-Fleshed Apples Modulate the Aorta and Heart Proteome in Hypercholesterolaemic Rats: The AppleCOR Study
Avocado 📋✍⛔37525782Effect of Avocado Consumption on Risk Factors of Cardiovascular Diseases: A Systematic Review and Meta-Analysis
Barberry 📋✍⛔36910359Berberis lyceum root bark extract attenuates anticancer drugs induced neurotoxicity and cardiotoxicity in rats
Bay Leaf 📋 ⛔32567295The effect of bay leaf extract (Syzygium polyanthum) on vascular endothelial growth factor (VEGF) and CD31 (PECAM-1) expression in acute coronary syndrome
Butyrate 📋 ⛔38176636Sodium butyrate alleviates right ventricular hypertrophy in pulmonary arterial hypertension by inhibiting H19 and affecting the activation of let-7g-5p/IGF1 receptor/ERK
Captopril 📋 38607208Correlation Between the Severity of Coronary Artery Disease and Retinal Artery Disease and the Therapeutic Effect of Captopril
Cardamom 📋✍⛔38593657Cardamom consumption may improve cardiovascular metabolic biomarkers in adults: A systematic review and meta-analysis of randomized controlled trials
Carrot 📋 ⛔33918417Carrot Supplementation Improves Blood Pressure and Reduces Aortic Root Lesions in an Atherosclerosis-Prone Genetic Mouse Model
Cordyceps 📋✍⛔36059969Bidirectional regulatory effects of Cordyceps on arrhythmia: Clinical evaluations and network pharmacology
Docosapentaenoic Acid 📋✍ 38117698Association between dietary omega-3 intake and coronary heart disease among American adults: The NHANES, 1999-2018
Eleuthero 📋✍⛔38380572Integrating serum pharmacochemistry and network pharmacology to explore the molecular mechanisms of Acanthopanax senticosus (Rupr. & Maxim.) Harms on attenuating doxorubicin-induced myocardial injury
Essential Oils 📋 ⛔37446792Aromatic Plant-Based Functional Foods: A Natural Approach to Manage Cardiovascular Diseases
Fat 📋 37836498Reassessing the Effects of Dietary Fat on Cardiovascular Disease in China: A Review of the Last Three Decades
Fig 📋 ⛔32946057Synergistic effects of Ficus Carica extract and extra virgin olive oil against oxidative injury, cytokine liberation, and inflammation mediated by 5-Fluorouracil in cardiac and renal tissues of male albino rats
Frankincense 📋✍⛔37086900Boswellia serrata inhibits LPS-induced cardiotoxicity in H9c2 cells: Investigating role of anti-inflammatory and antioxidant effects
Fufang Danshen 📋 34107328Chemical composition, quality control, pharmacokinetics, pharmacological properties and clinical applications of Fufang Danshen Tablet: A systematic review
Glycyrrhetinic Acid 📋 36070662Natural compound glycyrrhetinic acid protects against doxorubicin-induced cardiotoxicity by activating the Nrf2/HO-1 signaling pathway
Haritaki 📋✍⛔35400254Cardio-protective effects of Terminalia catappa leaves and Terminalia chebula fruit extract in doxorubicin-induced cardiomyopathy in rats
Hazelnut 📋 ⛔32742827A Pilot Study on the Effects of Nut Consumption on Cardiovascular Biomarkers
Inulin 📋✍⛔33641656The effects of co-administration of probiotics and prebiotics on chronic inflammation, and depression symptoms in patients with coronary artery diseases: a randomized clinical trial
L-Carnosine 📋✍⛔38348353Iron scavenging and suppression of collagen cross-linking underlie antifibrotic effects of carnosine in the heart with obesity
Licochalcones 📋 38078919Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway
Linalool 📋 ⛔33562483Cardioprotective Effect of Linalool against Isoproterenol-Induced Myocardial Infarction
Liquiritigenin 📋 35747908Liquiritigenin protects against myocardial ischemic by inhibiting oxidative stress, apoptosis, and L-type Ca 2+ channels
Loquat 📋✍⛔34878451A functional polysaccharide from Eriobotrya japonica relieves myocardial ischemia injury via anti-oxidative and anti-inflammatory effects
Mangosteen 📋✍⛔35904170The metabolic and molecular mechanisms of α‑mangostin in cardiometabolic disorders (Review)
Morin 📋 38331877Morin ameliorates myocardial injury in diabetic rats via modulation of inflammatory pathways
Neohesperidin 📋 33604646Neohesperidin alleviated pathological damage and immunological imbalance in rat myocardial ischemia-reperfusion injury via inactivation of JNK and NF-κB p65
Nicotinamide 📋✍⛔37713442Nicotinamide restores tissue NAD+ and improves survival in rodent models of cardiac arrest
Nootkatone 📋 36001774Nootkatone Ameliorates Doxorubicin Induced Myocardial Injury through Modulation of NF-κB Signals and Oxidative Stress
Olive Polyphenols 📋 32994927A review on management of cardiovascular diseases by olive polyphenols
Oolong Tea 📋 ⛔33338714Active food ingredients production from cold pressed processing residues of Camellia oleifera and Camellia sinensis seeds for regulation of blood pressure and vascular function
Papaya 📋✍⛔35215343Carpaine Promotes Proliferation and Repair of H9c2 Cardiomyocytes after Oxidative Insults
Perilla 📋✍ 37329971Perillaldehyde improves diabetic cardiomyopathy by upregulating miR-133a-3p to regulate GSK-3β
Phloretin 📋 37659297Phloretin alleviates doxorubicin-induced cardiotoxicity through regulating Hif3a transcription via targeting transcription factor Fos
Phytosterols 📋 38722432Unveiling the molecular mechanisms: dietary phytosterols as guardians against cardiovascular diseases
Psyllium 📋✍⛔31214288Supplementation With Psyllium Seed Husk Reduces Myocardial Damage in a Rat Model of ischemia/reperfusion
Royal Jelly 📋✍⛔38500210Cardioprotective role of royal jelly in the prevention of celecoxib-mediated cardiotoxicity in adult male albino rats
Safranal 📋 36586525Effect and mechanism of safranal on ISO-induced myocardial injury based on network pharmacology
Shogaol 📋 374324006-Shogaol, an Active Component of Ginger, Inhibits p300 Histone Acetyltransferase Activity and Attenuates the Development of Pressure-Overload-Induced Heart Failure
Soy Isoflavones 📋✍⛔36705465Soy isoflavone intake and risk of cardiovascular disease in adults: A systematic review and dose-response meta-analysis of prospective cohort studies
Stinging Nettle 📋✍⛔35189251Exercise and Urtica Dioica extract ameliorate mitochondrial function and the expression of cardiac muscle Nuclear Respiratory Factor 2 and Peroxisome proliferator-activated receptor Gamma Coactivator 1-alpha in STZ-induced diabetic rats
Syringic Acid 📋 35719043Syringic acid mitigates isoproterenol-induced cardiac hypertrophy and fibrosis by downregulating Ereg
Tannic Acid 📋✍⛔34080663Tannic acid alleviates lipopolysaccharide‑induced H9C2 cell apoptosis by suppressing reactive oxygen species‑mediated endoplasmic reticulum stress
Telmisartan 📋 ⛔37552407Telmisartan versus EnalapRil In heart failure with redUced ejection fraction patients with Moderately impaired kidney Functions; randomized controlled trial: "TRIUMF trial"
Trans-Resveratrol 📋 10219463Relaxant Effect of Trans-Resveratrol on Isolated Porcine Coronary Arteries
Vitamins 📋 37513682How Do Minerals, Vitamins, and Intestinal Microbiota Affect the Development and Progression of Heart Disease in Adult and Pediatric Patients?
Whey Protein 📋✍⛔36904293Benefits of Whey Proteins on Type 2 Diabetes Mellitus Parameters and Prevention of Cardiovascular Diseases
Withaferin A 📋 38727319Withaferin A as a Potential Therapeutic Target for the Treatment of Angiotensin II-Induced Cardiac Cachexia
Anethole 📋 35658236Anti-inflammatory effect of trans-anethol in a rat model of myocardial ischemia-reperfusion injury
Anthocyanidins 📋 37090778Association between dietary intake of anthocyanidins and heart failure among American adults: NHANES (2007-2010 and 2017-2018)
Apple Vinegar 📋✍⛔37608660The effects of apple cider vinegar on cardiometabolic risk factors: A systematic review and meta-analysis of clinical trials
Arachidonic Acid 📋✍⛔38336692Protective role of arachidonic acid against diabetic myocardial ischemic injury: a translational study of pigs, rats, and humans
Arctiin 📋 32135123Arctiin protects rat heart against ischemia/reperfusion injury via a mechanism involving reduction of necroptosis
Argan Oil 📋✍⛔30153577A comparative study on the effect of argan oil versus fish oil on risk factors for cardio-vascular disease in high-fat-fed rats
Astragalin 📋 30015889Astragalin and dihydromyricetin as adjuncts to histidine‑tryptophan‑ketoglutarate cardioplegia enhances protection during cardioplegic arrest
Balloon Flower 📋✍⛔38682702Platycodin D Ameliorates Type 2 Diabetes-Induced Myocardial Injury by Activating the AMPK Signaling Pathway
Beta-Carotene 📋✍⛔33361744Low Dose of β-Carotene Regulates Inflammation, Reduces Caspase Signaling, and Correlates with Autophagy Activation in Cardiomyoblast Cell Lines
Beta-Cryptoxanthin 📋 32362203β-cryptoxanthin alleviates myocardial ischaemia/reperfusion injury by inhibiting NF-κB-mediated inflammatory signalling in rats
Beta-Glucan 📋✍⛔35215555Natural Polysaccharide β-Glucan Protects against Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress
Beta-Lapachone 📋 35738116β-Lapachone, an NQO1 activator, alleviates diabetic cardiomyopathy by regulating antioxidant ability and mitochondrial function
Betulinic Acid 📋 36808036Betulinic acid protects against cardiotoxicity of the organophosphorus pesticide chlorpyrifos by suppressing oxidative stress, inflammation, and apoptosis in rats
Bilobalide 📋 37199885Bilobalide Prevents Apoptosis and Improves Cardiac Function in Myocardial Infarction
Blackcurrant 📋✍⛔34836432Blackcurrant Improves Diabetic Cardiovascular Dysfunction by Reducing Inflammatory Cytokines in Type 2 Diabetes Mellitus Mice
Boric Acid 📋✍⛔37562273Therapeutic role of boron on acrylamide-induced nephrotoxicity, cardiotoxicity, neurotoxicity, and testicular toxicity in rats: Effects on Nrf2/Keap-1 signaling pathway and oxidative stress
Boron 📋✍⛔34825958Plasma boron concentrations in the general population: a cross-sectional analysis of cardio-metabolic and dietary correlates
Boswellic Acid 📋✍⛔34275862Cardioprotective effect of boswellic acids against doxorubicin induced myocardial infarction in rats
Calcium 📋✍⛔38613076Association between Daily Dietary Calcium Intake and the Risk of Cardiovascular Disease (CVD) in Postmenopausal Korean Women
Cardamonin 📋 34766179Cardamonin inhibits osteogenic differentiation of human valve interstitial cells and ameliorates aortic valve calcification via interfering in the NF-κB/NLRP3 inflammasome pathway
Cherry 📋 ⛔35625374Anti-Inflammatory and Antioxidant Properties of Tart Cherry Consumption in the Heart of Obese Rats
Chia Seeds 📋 ⛔38316807Chia seeds ameliorate cardiac disease risk factors via alleviating oxidative stress and inflammation in rats fed high-fat diet
Chrysanthemum 📋✍⛔35158951Chrysanthemum morifolium Extract Ameliorates Doxorubicin-Induced Cardiotoxicity by Decreasing Apoptosis
Collagen 📋✍ 38140281Effects of Long-Term Administration of Bovine Bone Gelatin Peptides on Myocardial Hypertrophy in Spontaneously Hypertensive Rats
Coriander 📋 ⛔35011441Coriandrum sativum L.: A Review on Ethnopharmacology, Phytochemistry, and Cardiovascular Benefits
Coumaric acid 📋 38439645Cardioprotective effects of p-coumaric acid on tachycardia, inflammation, ion pump dysfunction, and electrolyte imbalance in isoproterenol-induced experimental myocardial infarction
Cryptotanshinone 📋 36743695Cryptotanshinone Attenuated Pathological Cardiac Remodeling In Vivo and In Vitro Experiments
Date 📋 ⛔35268000Methanolic Phoenix dactylifera L. Extract Ameliorates Cisplatin-Induced Hepatic Injury in Male Rats
Diallyl Disulfide 📋 34646139The Potential Benefits of Using Garlic Oil and Its Active Constituent, Dially Disulphide, in Combination With Carvedilol in Ameliorating Isoprenaline-Induced Cardiac Damage in Rats
Essential Amino Acids 📋✍⛔37242170Essential Amino Acids-Rich Diet Increases Cardiomyocytes Protection in Doxorubicin-Treated Mice
Essential Fatty Acids 📋✍ 34680583Essential Fatty Acids as Biomedicines in Cardiac Health
Garlic Oil 📋 ⛔34646139The Potential Benefits of Using Garlic Oil and Its Active Constituent, Dially Disulphide, in Combination With Carvedilol in Ameliorating Isoprenaline-Induced Cardiac Damage in Rats
Ginger extract 📋✍⛔33424327Ginger extract attenuates labetalol induced apoptosis, DNA damage, histological and ultrastructural changes in the heart of rat fetuses
Ginkgolic Acid 📋 29524504Pharmacological inhibition of SUMO-1 with ginkgolic acid alleviates cardiac fibrosis induced by myocardial infarction in mice
Glabridin 📋 30833897Glabridin Prevents Doxorubicin-Induced Cardiotoxicity Through Gut Microbiota Modulation and Colonic Macrophage Polarization in Mice
Glucosamine 📋✍⛔37422736Association Between Glucosamine Use and the Risk of Incident Heart Failure: The UK Biobank Cohort Study and Mendelian Randomization Analysis
Holy Basil 📋✍⛔26665293Amelioration of Inflammation by Phenolic Rich Methanolic Extract of Ocimum Sanctum Linn. Leaves in Isoproterenol Induced Myocardial Infarction
Honey 📋✍⛔32207479Chemical basis of hawthorn processed with honey protecting against myocardial ischaemia
Jasmine 📋 ⛔34577135Jasminum sambac: A Potential Candidate for Drug Development to Cure Cardiovascular Ailments
Jujube 📋 ⛔35783519Jujuboside A Ameliorates Myocardial Apoptosis and Inflammation in Rats with Coronary Heart Disease by Inhibiting PPAR- α Signaling Pathway
Knotweed 📋✍⛔35669500Investigation of the Potential Key Genes and the Multitarget Mechanisms of Polygonum cuspidatum against Heart Failure Based on Network Pharmacology and Experimental Validation
Krill Oil 📋✍⛔35057549Krill Oil Inhibits NLRP3 Inflammasome Activation in the Prevention of the Pathological Injuries of Diabetic Cardiomyopathy
L-Histidine 📋✍⛔34273376Effects of aerobic and resistance exercise training associated with carnosine precursor supplementation on maximal strength and V̇O 2max in rats with heart failure
L-Proline 📋✍⛔32492448Proline Improves Cardiac Remodeling Following Myocardial Infarction and Attenuates Cardiomyocyte Apoptosis via Redox Regulation
Lavender Essential Oil 📋✍⛔35655588Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway
Linoleic Acid 📋✍⛔35380474Blood levels of omega-6 fatty acids and coronary heart disease: a systematic review and metaanalysis of observational epidemiology
Lotus 📋 ⛔35280514Acacetin as a Potential Protective Compound against Cardiovascular Diseases
Marjoram 📋 ⛔34547419Marjoram extract prevents ischemia reperfusion-induced myocardial damage and exerts anti-contractile effects in aorta segments of male wistar rats
Milk 📋 ⛔35268066Cow's Milk Intake and Risk of Coronary Heart Disease in Korean Postmenopausal Women
Nitrate 📋✍⛔38472804The Cardioprotective Role of Nitrate-Rich Vegetables
Oleanolic Acid 📋 35346820Pentacyclic triterpene oleanolic acid protects against cardiac aging through regulation of mitophagy and mitochondrial integrity
Oleic Acid 📋 ⛔32724624High dietary oleic acid in olive oil-supplemented diet enhanced omega-3 fatty acid in blood plasma of rats
Olive 📋✍⛔38704428Olive oil consumption is associated with lower cancer, cardiovascular and all-cause mortality among Italian adults: prospective results from the Moli-sani Study and analysis of potential biological mechanisms
Peony 📋 ⛔37831380Total Glucosides of Paeony Ameliorate Myocardial Injury in Chronic Heart Failure Rats by Suppressing PARP-1
Phosphatidylserine 📋✍⛔33922385Phosphatidylserine Supplementation as a Novel Strategy for Reducing Myocardial Infarct Size and Preventing Adverse Left Ventricular Remodeling
Piperlongumine 📋 33497927Piperlongumine attenuates angiotensin-II-induced cardiac hypertrophy and fibrosis by inhibiting Akt-FoxO1 signalling
Pistachio 📋✍⛔36856595Cardioprotective Effect of Pistacia vera L. (Green Pistachio) Hull Extract in Wistar Albino Rats with Doxorubicin-Induced Cardiac Damage
Plum 📋 ⛔33978491Dried Plum Consumption Improves Total Cholesterol and Antioxidant Capacity and Reduces Inflammation in Healthy Postmenopausal Women
Pomegranate Seed extract 📋 ⛔35782771Pomegranate seed oil protects against tacrolimus-induced toxicity in the heart and kidney by modulation of oxidative stress in rats
Prebiotics 📋✍⛔38411391Advancing lifelong precision medicine for cardiovascular diseases through gut microbiota modulation
Prunella Vulgaris 📋✍⛔37992723Phenolic acids from Prunella vulgaris alleviate cardiac remodeling following myocardial infarction partially by suppressing NLRP3 activation
Quercitrin 📋 38447360Quercitrin improves cardiac remodeling following myocardial infarction by regulating macrophage polarization and metabolic reprogramming
Scutellarein 📋 38516760Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress
Skullcap 📋✍⛔36152591Pharmacological properties of total flavonoids in Scutellaria baicalensis for the treatment of cardiovascular diseases
Sodium Bicarbonate 📋✍⛔37921685Sodium Bicarbonate and Calcium Chloride for the Treatment of Hyperkalemia-Induced Cardiac Arrest: A Randomized, Blinded, Placebo-Controlled Animal Study
Soybean Oil 📋 ⛔34171740Soybean oil lowers circulating cholesterol levels and coronary heart disease risk, and has no effect on markers of inflammation and oxidation
Spices 📋 37236043Potential benefits of spicy food consumption on cardiovascular outcomes in patients with diabetes: A cohort study of the China Kadoorie Biobank
Star Fuit 📋 ⛔31733577Effect of an aqueous extract of Averrhoa carambola L. on endothelial function in rats with ventricular remodelling
Stevia 📋✍⛔35588653Stevia rebaudiana Bertoni and its secondary metabolites: Their effects on cardiovascular risk factors
Strawberry 📋✍⛔27464461Effects of a dietary strawberry powder on parameters of vascular health in adolescent males
Tea Polyphenols 📋 37448666Protective effects and molecular mechanisms of tea polyphenols on cardiovascular diseases
Thyme 📋✍⛔35228189Cardioprotective potential of Thymus linearis Benth
Thymol 📋✍⛔32715125Cardioprotective effect of thymol against adrenaline-induced myocardial injury in rats
Turmeric 📋✍⛔34106380Turmeric and its bioactive constituents trigger cell signaling mechanisms that protect against diabetes and cardiovascular diseases
Vitamin B5 📋✍⛔3590676[Therapeutic efficacy of pantothenic acid preparations in ischemic heart disease patients]
Wormwood 📋✍⛔37898972Mechanism of Artemisia annua L. in the treatment of acute myocardial infarction: network pharmacology, molecular docking and in vivo validation
Yogurt 📋 ⛔36349966Yogurt consumption and risk of mortality from all causes, cardiovascular disease, and cancer: a comprehensive systematic review and dose-response meta-analysis of cohort studies
5-HTP 📋✍⛔384626935-Hydroxytryptophan acts as a gap junction inhibitor to limit the spread of chemotherapy-induced cardiomyocyte injury and mitochondrial dysfunction
Aloe Vera 📋✍⛔34355443Potential protective effects of Aloe vera gel on cardiovascular diseases: A mini-review
Apricot Oil 📋 ⛔21896302Protective Effects of Apricot Kernel Oil on Myocardium Against Ischemia-Reperfusion Injury in Rats
Bacopa Monnieri 📋✍⛔15934019Antioxidant activity of DHC-1, an herbal formulation, in experimentally-induced cardiac and renal damage
BCAA 📋✍⛔34789638The Effects of an Oral Nutritional Supplement with Whey Peptides and Branched-Chain Amino Acids for Cardiac Rehabilitation of Patients with Chronic Heart Failure
Bean 📋 ⛔36963901Beans comsumption can contribute to the prevention of cardiovascular disease
Bee Venom 📋✍⛔34550826Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats
Beer 📋 36615830Features of Non-Alcoholic Beer on Cardiovascular Biomarkers. Can It Be a Substitute for Conventional Beer?
Beta-Alanine 📋✍⛔34273376Effects of aerobic and resistance exercise training associated with carnosine precursor supplementation on maximal strength and V̇O 2max in rats with heart failure
Bile Salts 📋 38180064Bile salt signaling and bile salt-based therapies in cardiometabolic disease
Bitter Melon 📋✍⛔31823659Modulatory effects of stonebreaker ( Phyllanthus amarus) and bitter gourd ( Momordica charantia) on enzymes linked with cardiac function in heart tissue of doxorubicin-stressed rats
Bitter Orange 📋✍⛔32438719Effect of a Combination of Citrus Flavones and Flavanones and Olive Polyphenols for the Reduction of Cardiovascular Disease Risk: An Exploratory Randomized, Double-Blind, Placebo-Controlled Study in Healthy Subjects
Black Pepper 📋✍⛔37299525Combination of Taurine and Black Pepper Extract as a Treatment for Cardiovascular and Coronary Artery Diseases
Black Tea Polyphenols 📋 24172295Interactions of black tea polyphenols with human gut microbiota: implications for gut and cardiovascular health
Blackberry 📋 ⛔35487829Raspberry and blackberry act in a synergistic manner to improve cardiac redox proteins and reduce NF-κB and SAPK/JNK in mice fed a high-fat, high-sucrose diet
Brazil Nut 📋 ⛔31585864Anti-atherosclerotic and cardiovascular protective benefits of Brazilian nuts
Burdock 📋 ⛔33864278Polyphenols from Arctium lappa L ameliorate doxorubicin-induced heart failure and improve gut microbiota composition in mice
Butter 📋 ⛔37671505High consumption of dairy products and risk of major adverse coronary events and stroke in a Swedish population
Cabbage 📋 ⛔38327044Protective effect of diindolylmethane-enriched dietary cabbage against doxorubicin-induced cardiotoxicity in mice
Caffeic Acid 📋✍⛔33343392Cardiovascular Effects of Caffeic Acid and Its Derivatives: A Comprehensive Review
Cantaloupe 📋 ⛔38348351Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics and in silico electrophysiological models
Caraway 📋 ⛔36284942Effect of Caraway Seed Extract on the Blood Biochemistry and Antioxidant Capacity among the Hyperoxidative Stress-Induced Rats
Carnosol 📋 38692016Carnosol attenuates angiotensin II-induced cardiac remodeling and inflammation via directly binding to p38 and inhibiting p38 activation
Castor Oil 📋✍⛔38696683Methanolic Extract of Ricinus Communis ameliorated cardiovascular dysfunction in dichlorvos-exposed rats
Chaga Mushrooms 📋✍⛔33236154Inonotus obliquus extract alleviates myocardial ischemia/reperfusion injury by suppressing endoplasmic reticulum stress
Chicoric Acid 📋 37951150Chicoric acid ameliorates sepsis-induced cardiomyopathy via regulating macrophage metabolism reprogramming
Chlorella 📋✍⛔37018990The effects of Chlorella vulgaris on cardiovascular risk factors: A comprehensive review on putative molecular mechanisms
Chromium 📋✍⛔37809394The role of chromium supplementation in cardiovascular risk factors: A comprehensive reviews of putative molecular mechanisms
Clove 📋 ⛔15934019Antioxidant activity of DHC-1, an herbal formulation, in experimentally-induced cardiac and renal damage
Conjugated Linoleic Acid 📋✍⛔19935865Human Health Benefits of Vaccenic Acid
Cornus 📋 37813285Loganin protects against myocardial ischemia-reperfusion injury by modulating oxidative stress and cellular apoptosis via activation of JAK2/STAT3 signaling
Costus 📋✍⛔34262464Therapeutic Impact of Costus ( Saussurea lappa) Against Ehrlich Solid Tumor-Induced Cardiac Toxicity and DNA Damage in Female Mice
Creatine 📋✍⛔34684484Cardiac Oxidative Stress and the Therapeutic Approaches to the Intake of Antioxidant Supplements and Physical Activity
Cyanidin 📋✍ 38349396Cyanidin prevents cardiomyocyte apoptosis in mice after myocardial infarction
D-Limonene 📋✍⛔35843301S-limonene protects the heart in an experimental model of myocardial infarction induced by isoproterenol: Possible involvement of mitochondrial reactive oxygen species
Diallyl Sulfide 📋 34651661Diallyl sulfide protects against dilated cardiomyopathy via inhibition of oxidative stress and apoptosis in mice
DIM 📋✍⛔38327044Protective effect of diindolylmethane-enriched dietary cabbage against doxorubicin-induced cardiotoxicity in mice
Echinacea 📋✍⛔26369808Avemar and Echinacea Extracts Enhance Mobilization and Homing of CD34(+) Stem Cells in Rats With Acute Myocardial Infarction
Elastin 📋✍ 34917605Elastin Structure, Synthesis, Regulatory Mechanism and Relationship With Cardiovascular Diseases
Eucalyptus 📋✍⛔34270371Upregulation of PCSK9, rho kinase and cardiac troponin by Eucalyptus globulus leaf extract improves fructose-streptozotocin-induced diabetic cardiac dysfunction in rats
Eucommia 📋✍⛔37889854Cardioprotection of Eucommiae Folium: the extract and pharmaceutically active compounds attenuate hyperglycemia, mitochondrial dysfunction, calcium dyshomeostasis, insulin resistance, and oxidative stress in diabetic cardiomyopathy db/db mice
Evening Primrose Oil 📋✍⛔24665356Evening primrose oil ameliorates platelet aggregation and improves cardiac recovery in myocardial-infarct hypercholesterolemic rats
Fennel 📋✍⛔38678740Fennel seeds extract prevents fructose-induced cardiac dysfunction in a rat model of metabolic syndrome via targeting abdominal obesity, hyperuricemia and NF-κβ inflammatory pathway
Fermented Foods 📋 ⛔36204374Fermented foods and cardiometabolic health: Definitions, current evidence, and future perspectives
Flavones 📋 34858167Navigating Calcium and Reactive Oxygen Species by Natural Flavones for the Treatment of Heart Failure
Forskolin 📋✍⛔33564685Forskolin Protected against Streptozotocin-Induced Diabetic Cardiomyopathy via Inhibition of Oxidative Stress and Cardiac Fibrosis in Mice
GABA 📋✍⛔38487926Prophylactic Supplementation with Lactobacillus Reuteri or Its Metabolite GABA Protects Against Acute Ischemic Cardiac Injury
Galangal 📋✍⛔32841691Adipose derived mesenchymal stem cells along with Alpinia oxyphylla extract alleviate mitochondria-mediated cardiac apoptosis in aging models and cardiac function in aging rats
Genipin 📋 36445232POTENTIAL CARDIOPROTECTIVE EFFECT OF GENIPIN VIA CYCLOOXIDASE 2 SUPPRESSION AND P53 SIGNAL PATHWAY ATTENUATION IN INDUCED MYOCARDIAL INFARCTION IN RATS
Geraniin 📋 35461005Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice
Giloy 📋✍⛔37907489Cardioprotective Role of Tinospora cordifolia against Trimethylamine-NOxide and Glucose Induced Stress in Rat Cardiomyocytes
Ginkgetin 📋 30582212Ginkgetin aglycone attenuates the apoptosis and inflammation response through nuclear factor-kB signaling pathway in ischemic-reperfusion injury
Glycine 📋✍⛔37805752[Effects and mechanism of glycine on rat cardiomyocytes pretreated with serum from burned rats]
Grapefruit 📋 ⛔27134462Antihyperlipidemic effects of Citrus sinensis, Citrus paradisi, and their combinations
Helichrysum 📋 ⛔35495751Alleviation of Myocardial Inflammation in Diabetic Rats by Flavonoid Extract of Helichrysum Arenarium and Its Effect on Damaged Myocardial Cells Induced by High Glucose
Horny Goat Weed 📋✍⛔35442463The mechanism of Epimedium in the treatment of coronary atherosclerotic heart disease based on network pharmacology, molecular docking, and in vitro studies
Hypericin 📋 38547517Hypericin alleviates Chronic Kidney Disease induced Left Ventricular Hypertrophy via regulation of FGF23-FGFR4 signaling pathway
Indian Mulberry 📋✍⛔36866542The Investigation of the Molecular Mechanism of Morinda officinalis How in the Treatment of Heart Failure
Isoquercitrin 📋 32388479Targeting Casein Kinase 2 With Quercetin or Enzymatically Modified Isoquercitrin as a Strategy for Boosting the Type 1 Interferon Response to Viruses and Promoting Cardiovascular Health
Kacip Fatimah 📋✍⛔25786162Protective effects of Labisia pumila var. alata on biochemical and histopathological alterations of cardiac muscle cells in isoproterenol-induced myocardial infarction rats
L-Lysine 📋✍⛔34265467Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR-v-ATPase axis
L-Theanine 📋✍⛔38677602L-theanine abates oxidative stress and mitochondrial dysfunction in myocardial ischemia-reperfusion injury by positively regulating the antioxidant response
L-Tryptophan 📋✍⛔34576067Tryptophan: From Diet to Cardiovascular Diseases
Lactobacillus plantarum 📋 ⛔32446786From the gut to the heart: L. plantarum and inulin administration as a novel approach to control cardiac apoptosis via 5-HT2B and TrkB receptors in diabetes
Lemongrass Essential Oil 📋✍⛔38639827Cardioprotective Potential of Cymbopogon citratus Essential Oil against Isoproterenol-induced Cardiomyocyte Hypertrophy: Possible Involvement of NLRP3 Inflammasome and Oxidative Phosphorylation Complex Subunits
Ligustilide 📋 24944617Effect of ligustilide on Ang II-induced hypertrophy in cardiomyocytes and the potential mechanisms
Maca Root 📋✍⛔34765511Lepidium meyenii (maca) and soy isoflavones reduce cardiac stunning of ischemia-reperfusion in rats by mitochondrial mechanisms
Madecassoside 📋 31539918Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review
Magnolia 📋✍⛔31749425Cardiovascular Modulating Effects of Magnolol and Honokiol, Two Polyphenolic Compounds from Traditional Chinese Medicine-Magnolia Officinalis
Mango Leaf 📋 ⛔28894627Mangifera indica L. leaf extract alleviates doxorubicin induced cardiac stress
Milk Thistle 📋✍⛔33857761Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum
Morusin 📋 38502885Morusin Alleviates Aortic Valve Calcification by Inhibiting Valve Interstitial Cell Senescence Through Ccnd1/Trim25/Nrf2 Axis
Motherwort 📋✍⛔38732560Characterizations of White Mulberry, Sea-Buckthorn, Garlic, Lily of the Valley, Motherwort, and Hawthorn as Potential Candidates for Managing Cardiovascular Disease-In Vitro and Ex Vivo Animal Studies
MSM 📋✍⛔30038844Methylsulfonylmethane decreases inflammatory response to tumor necrosis factor-α in cardiac cells
MUFA 📋 ⛔26016869Replacement of saturated with unsaturated fats had no impact on vascular function but beneficial effects on lipid biomarkers, E-selectin, and blood pressure: results from the randomized, controlled Dietary Intervention and VAScular function (DIVAS) study
Myrrh Essential Oil 📋 ⛔33421599Protective effects of Myrrh essential oil on isoproterenol-induced myocardial infarction in rats through antioxidant, anti-inflammatory, Nrf2/HO-1 and apoptotic pathways
Oak Bark 📋✍⛔22105311Cardioprotective and hepatoprotective effects of ellagitannins from European oak bark (Quercus petraea L.) extract in rats
Oats 📋 ⛔32728751Global review of heart health claims for oat beta-glucan products
Omega-6 Fatty Acids 📋✍⛔33693794Plasma ω-3 and ω-6 PUFA Concentrations and Risk of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis
Patchouli 📋✍⛔25829770Effects of Pogostemon cablin Blanco extract on hypoxia induced rabbit cardiomyocyte injury
Peach 📋 ⛔25801980Consumption of polyphenol-rich peach and plum juice prevents risk factors for obesity-related metabolic disorders and cardiovascular disease in Zucker rats
Peas 📋 ⛔34649330Pea (Pisum sativum) peel extract attenuates DOX-induced oxidative myocardial injury
Pecan 📋 ⛔34841598Pecan-enriched diets increase energy expenditure and fat oxidation in adults at-risk for cardiovascular disease in a randomised, controlled trial
Persimmon 📋 ⛔35509232Protective Role of Diospyros lotus L. in Cisplatin-Induced Cardiotoxicity: Cardiac Damage and Oxidative Stress in Rats
Phosphatidylcholine 📋✍⛔34990309Effect of soya phosphatidylcholine and possible underlying mechanism on ischemia/reperfusion injury in isolated perfused rat heart: an experimental and computational study
Phytoestrogens 📋 ⛔35668938A Systematic Review and Meta-Analysis of Phytoestrogen Protects Against Myocardial Ischemia/Reperfusion Injury: Pre-Clinical Evidence From Small Animal Studies
Pomelo 📋 ⛔23401708Pummelo protects Doxorubicin-induced cardiac cell death by reducing oxidative stress, modifying glutathione transferase expression, and preventing cellular senescence
Poria Mushrooms 📋✍ 38212001[Effect and mechanism of Poria cocos polysaccharides on myocardial cell apoptosis in rats with myocardial ischemia-reperfusion injury by regulating Rho-ROCK signaling pathway]
Potato 📋 ⛔36856829Prospective cohort study on potato intake and mortality from cardiovascular diseases: the Japan Collaborative Cohort Study (JACC study)
Pregnenolone 📋✍⛔37242448Pregnenolone Inhibits Doxorubicin-Induced Cardiac Oxidative Stress, Inflammation, and Apoptosis-Role of Matrix Metalloproteinase 2 and NADPH Oxidase 1
Prickly Pear 📋 ⛔27595296Fruit vinegars attenuate cardiac injury via anti-inflammatory and anti-adiposity actions in high-fat diet-induced obese rats
Proanthocyanidins 📋 36271618Alternation of heart microRNA-mRNA network by high-intensity interval training and proanthocyanidin in myocardial ischemia rats: Artificial intelligence and validation experimental
Procyanidins 📋 ⛔37885736Protective effect and mechanism of procyanidin B2 against hypoxic injury of cardiomyocytes
Rapeseed Oil 📋✍ 33127255The effects of Canola oil on cardiovascular risk factors: A systematic review and meta-analysis with dose-response analysis of controlled clinical trials
Rhubarb 📋 ⛔35631194A Review on Rhubarb-Derived Substances as Modulators of Cardiovascular Risk Factors-A Special Emphasis on Anti-Obesity Action
Rice 📋 ⛔34636986Rice (Oryza sativa L.) bran preserves cardiac function by modulating pro-inflammatory cytokines and redox state in the myocardium from obese rats
Rosehip 📋✍⛔33510877Cardioprotective effect of Rosa canina L. methanolic extract on heat shock induced cardiomyocyte injury: An experimental study
Sage 📋✍⛔38472741Sage (Salvia officinalis) alleviates trazadone induced rat cardiotoxicity mediated via modulation of autophagy and oxidative stress
Salt 📋 ⛔34398440Chloride in Heart Failure Syndrome: Its Pathophysiologic Role and Therapeutic Implication
SAMe 📋✍⛔34192296Association between plasma S-adenosylmethionine and risk of mortality in patients with coronary artery disease: A cohort study
Sardine 📋 ⛔36860672Cardiovascular and lipid-lowering effects of a marine lipoprotein extract in a high-fat diet-induced obesity mouse model
Seaweeds 📋 ⛔36977879Seaweed Sargassum aquifolium extract ameliorates cardiotoxicity induced by doxorubicin in rats
Sesame 📋✍⛔33612009Clinical evidence of dietary supplementation with sesame on cardiovascular risk factors: An updated meta-analysis of randomized controlled trials
Shilajit 📋✍⛔24448712Cardioprotective effect of mumie (shilajit) on experimentally induced myocardial injury
St. Johns Wort 📋✍⛔31894670[Effects of hypericum perforatum extract on the immunogenic myocardial fibrosis in mice and its mechanism]
Sugarcane 📋 ⛔38027563Sugarcane leaf polysaccharide exerts a therapeutic effect on cardiovascular diseases through necroptosis
Sweet Potato 📋 ⛔34287964Anthocyanins from purple sweet potato alleviate doxorubicin-induced cardiotoxicity in vitro and in vivo
Theaflavins 📋✍ 35406003The Prevention Role of Theaflavin-3,3'-digallate in Angiotensin II Induced Pathological Cardiac Hypertrophy via CaN-NFAT Signal Pathway
Theobromine 📋✍⛔25869509Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation
Turkey Tail Mushrooms 📋 ⛔37375735Characterization, In Vitro Biological Activity and In Vivo Cardioprotective Properties of Trametes versicolor (L.:Fr.) Quél. Heteropolysaccharides in a Rat Model of Metabolic Syndrome
Vitamin A 📋✍⛔36399384Vitamin A Preserves Cardiac Energetic Gene Expression in a Murine Model of Diet-Induced Obesity
Vitamin B8 📋✍⛔32590101Myo-inositol and D-chiro-inositol Oral Supplementation Ameliorate Cardiac Dysfunction and Remodeling in a Mouse Model of Diet-Induced Obesity
Vitamin K2 mk-4 📋✍ 36857749Potential cardioprotective role of menaquinone-4 against cardiac ischemia-reperfusion injury
Vitamin K2 mk-7 📋✍ 32549853Highlighting The Substantial Body Of Evidence Confirming The Importance Of Vitamin K2 As A Cardio-Support Nutrient, And How The Right K2 Makes All The Difference
Yam 📋 37453145UPLC-Q TOF-MS-Based metabolomics and anti-myocardial ischemia activity of Dioscoreae Nipponicae Rhizoma from different geographical origins
Yerba Mate 📋✍⛔35373729Multigenomic modifications in human circulating immune cells in response to consumption of polyphenol rich extract of yerba mate ( Ilex paraguariensis A. St.-Hil.) are suggestive of cardiometabolic protective effects
Yohimbine 📋✍ 38466531Yohimbine Treatment Alleviates Cardiac Inflammation/Injury and Improves Cardiac Hemodynamics by Modulating Pro-Inflammatory and Oxidative Stress Indicators
Zeaxanthin 📋✍⛔36913015Zearalenone induces the senescence of cardiovascular cells in vitro and in vivo